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1

The Systems Biology Graphical Notation

Novère, Nicolas Le, Hucka, Michael, Mi, Huaiyu, Moodie, Stuart, Schreiber, Falk, Sorokin, Anatoly, Demir, Emek, Wegner, Katja, Aladjem, Mirit I, Wimalaratne, Sarala M

Journal:

Nature Biotechnology

Année:

2009

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2009

2

Quick tips for creating effective and impactful biological pathways using the Systems Biology Graphical Notation

Touré, Vasundra, Le Novère, Nicolas, Waltemath, Dagmar, Wolkenhauer, Olaf, Ouellette, Francis

Journal:

PLoS Computational Biology

Année:

2018

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2018

3

10.1038/19756

Changeux, Jean-Pierre, Marubio, Lisa M., Arroyo-Jimenez, Maria del Mar, Cordero-Erausquin, Matilde, Léna, Clément, Novère, Nicolas Le, d'Exaerde, Alban de Kerchove, Huchet, Monique, Damaj, M. Imad

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 458 KB

english, 1999

4

Erratum: The Systems Biology Graphical Notation

Le Novère, Nicolas, Hucka, Michael, Mi, Huaiyu, Moodie, Stuart, Schreiber, Falk, Sorokin, Anatoly, Demir, Emek, Wegner, Katja, Aladjem, Mirit I, Wimalaratne, Sarala M

Journal:

Nature Biotechnology

Année:

2009

Langue:

english

Fichier:

PDF, 65 KB

english, 2009

5

Nicotinic Receptors at the Amino Acid Level

Corringer, Pierre-Jean, Novère, Nicolas Le, Changeux, Jean-Pierre

Journal:

Annual Review of Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 418 KB

english, 2000

6

Quantitative and logic modelling of molecular and gene networks

Le Novère, Nicolas

Journal:

Nature Reviews Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 581 KB

english, 2015

7

Involvement of α6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion

Le Novère, Nicolas, Zoli, Michele, Léna, Clément, Ferrari, Rosaria, Picciott, Marina R., Merlo-Pich, Emilio, Changeux, Jean-Pierre

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 273 KB

english, 1999

8

Neuroscience Databases: Tools for Exploring Brain Structure-Function Relationships || The Ligand Gated Ion Channel Database: An Example of a Sequence Database in Neuroscience

Nicolas Le Novère and Jean-Pierre Changeux

Journal:

Philosophical Transactions Biological Sciences

Année:

2001

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2001

9

“Big Data” in neuroscience: open door to a more comprehensive and translational research

Lloret-Villas, Audald, Daudin, Rachel, Le Novère, Nicolas

Journal:

Big Data Analytics

Année:

2016

Langue:

english

Fichier:

PDF, 2.39 MB

english, 2016

10

Systems Biology Graphical Notation: Entity Relationship language Level 1 Version 2

Sorokin, Anatoly, Le Novère, Nicolas, Luna, Augustin, Czauderna, Tobias, Demir, Emek, Haw, Robin, Mi, Huaiyu, Moodie, Stuart, Schreiber, Falk, Villéger, Alice

Journal:

Journal of Integrative Bioinformatics

Année:

2015

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2015

11

Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration

Bargehr, Johannes, Ong, Lay Ping, Colzani, Maria, Davaapil, Hongorzul, Hofsteen, Peter, Bhandari, Shiv, Gambardella, Laure, Le Novère, Nicolas, Iyer, Dharini, Sampaziotis, Fotios, Weinberger, Florian,

Journal:

Nature Biotechnology

Année:

2019

Langue:

english

Fichier:

PDF, 4.16 MB

english, 2019

12

LibSBGN: Electronic Processing of SBGN maps

Demir, Emek, Dogrusoz, Ugur, Le Novère, Nicolas, Matsuoka, Yukiko, Sorokin, Anatoly, Funahashi, Akira, Mi, Huaiyu, Kitano, Hiroaki, Aladjem, Mirit, van Iersel, Martijn, Blinov, Michael, Boyd, Sarah, V

Journal:

Bioentrepreneur

Année:

2010

Fichier:

PDF, 1.38 MB

2010

13

Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]α-bungarotoxin binding sites in the brain of Macaca mulatta

Zhi-Yan Han, Michele Zoli, Ana Cardona, Jean-Pierre Bourgeois, Jean-Pierre Changeux, Nicolas Le Novère

Journal:

The Journal of Comparative Neurology

Année:

2003

Langue:

english

Fichier:

PDF, 556 KB

english, 2003

14

The diversity of subunit composition in nAChRs: Evolutionary origins, physiologic and pharmacologic consequences

Nicolas Le Novère, Pierre-Jean Corringer, Jean-Pierre Changeux

Journal:

Developmental Neurobiology

Année:

2002

Langue:

english

Fichier:

PDF, 229 KB

english, 2002

15

Localization of nAChR subunit mRNAs in the brain of Macaca mulatta

Zhi-Yan Han, Nicolas Le Novère, Michele Zoli, Joseph A. Hill Jr, Nicolas Champtiaux, Jean-Pierre Changeux

Journal:

European Journal of Neuroscience

Année:

2000

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2000

16

New Otx2 mRNA isoforms expressed in the mouse brain

Virginie Courtois, Gilles Chatelain, Zhi-Yan Han, Nicolas Le Novère, Gilbert Brun, Thomas Lamonerie

Journal:

Journal of Neurochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 452 KB

english, 2003

17

Software that goes with the flow in systems biology

Michael Hucka, Nicolas Le Novère

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 258 KB

english, 2010

18

BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models

Chen Li, Marco Donizelli, Nicolas Rodriguez, Harish Dharuri, Lukas Endler, Vijayalakshmi Chelliah, Lu Li, Enuo He, Arnaud Henry, Melanie I Stefan, Jacky L Snoep, Michael Hucka, Nicolas Le Novère, Cami

Journal:

BMC Systems Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2010

19

Looking inside the box: bacterial transistor arrays

Thomas S. Shimizu, Nicolas Le Novère

Journal:

Molecular Microbiology

Année:

2008

Langue:

english

Fichier:

PDF, 179 KB

english, 2008

20

Neuronal Nicotinic Receptor a6 Subunit mRNA is Selectively Concentrated in Catecholaminergic Nuclei of the Rat Brain

Nicolas Le Novere, Michele Zoli, Jean-Pierre Changeux

Journal:

European Journal of Neuroscience

Année:

1996

Langue:

english

Fichier:

PDF, 3.43 MB

english, 1996

21

10.1038/35041030

Bray, Dennis, Simon Shimizu, Thomas, Le Novère, Nicolas, Daniel Levin, Matthew, Beavil, Andrew J., Sutton, Brian J.

Journal:

Nature Cell Biology

Année:

2000

Langue:

english

Fichier:

PDF, 576 KB

english, 2000

22

10.1038/78124

Rogner, Ute C., Spyropoulos, Demetri D., Le Novère, Nicolas, Changeux, Jean-Pierre, Avner, Philip

Journal:

Nature Genetics

Année:

2000

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2000

23

Minimum information requested in the annotation of biochemical models (MIRIAM)

Novère, Nicolas Le, Finney, Andrew, Hucka, Michael, Bhalla, Upinder S, Campagne, Fabien, Collado-Vides, Julio, Crampin, Edmund J, Halstead, Matt, Klipp, Edda, Mendes, Pedro

Journal:

Nature Biotechnology

Année:

2005

Langue:

english

Fichier:

PDF, 216 KB

english, 2005

24

Novel pharmacological targets for the treatment of Parkinson's disease

Schapira, Anthony H. V., Bezard, Erwan, Brotchie, Jonathan, Calon, Frédéric, Collingridge, Graham L., Ferger, Borris, Hengerer, Bastian, Hirsch, Etienne, Jenner, Peter, Novère, Nicolas Le

Journal:

Nature Reviews Drug Discovery

Année:

2006

Langue:

english

Fichier:

PDF, 655 KB

english, 2006

25

Ranked retrieval of Computational Biology models

Ron Henkel, Lukas Endler, Andre Peters, Nicolas Le Novère, Dagmar Waltemath

Journal:

BMC Bioinformatics

Année:

2010

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2010

26

The Molecular Pages of the mesotelencephalic dopamine consortium (DopaNet)

Nicolas Le Novère, Marco Donizelli

Journal:

BMC Bioinformatics

Année:

2004

Langue:

english

Fichier:

PDF, 277 KB

english, 2004

27

SBMLeditor: effective creation of models in the Systems Biology Markup Language (SBML)

Nicolas Rodriguez, Marco Donizelli, Nicolas Le Novère

Journal:

BMC Bioinformatics

Année:

2007

Langue:

english

Fichier:

PDF, 490 KB

english, 2007

28

Model storage, exchange and integration

Nicolas Le Novère

Journal:

BMC Neuroscience

Année:

2006

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2006

29

MIRIAM Resources: tools to generate and resolve robust cross-references in Systems Biology

Camille Laibe, Nicolas Le Novère

Journal:

BMC Systems Biology

Année:

2007

Langue:

english

Fichier:

PDF, 799 KB

english, 2007

30

The long journey to a Systems Biology of neuronal function

Nicolas Le Novère

Journal:

BMC Systems Biology

Année:

2007

Langue:

english

Fichier:

PDF, 215 KB

english, 2007

31

Molecules for memory: modelling CaMKII

Melanie Stefan, Nicolas Le Novere

Journal:

BMC Systems Biology

Année:

2007

Langue:

english

Fichier:

PDF, 138 KB

english, 2007

32

Computing phenomenologic Adair-Klotz constants from microscopic MWC parameters

Melanie I Stefan, Stuart J Edelstein, Nicolas Le Novère

Journal:

BMC Systems Biology

Année:

2009

Langue:

english

Fichier:

PDF, 464 KB

english, 2009

33

Meredys, a multi-compartment reaction-diffusion simulator using multistate realistic molecular complexes

Dominic P Tolle, Nicolas Le Novère

Journal:

BMC Systems Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2010

34

Brownian diffusion of AMPA receptors is sufficient to explain fast onset of LTP

Dominic P Tolle, Nicolas Le Novère

Journal:

BMC Systems Biology

Année:

2010

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2010

35

Reproducible computational biology experiments with SED-ML - The Simulation Experiment Description Markup Language

Dagmar Waltemath, Richard Adams, Frank T Bergmann, Michael Hucka, Fedor Kolpakov, Andrew K Miller, Ion I Moraru, David Nickerson, Sven Sahle, Jacky L Snoep, Nicolas Le Novère

Journal:

BMC Systems Biology

Année:

2011

Langue:

english

Fichier:

PDF, 927 KB

english, 2011

36

Comparative models of P2X2 receptor support inter-subunit ATP-binding sites

Guillaume Guerlet, Antoine Taly, Lia Prado de Carvalho, Adeline Martz, Ruotian Jiang, Alexandre Specht, Nicolas Le Novère, Thomas Grutter

Journal:

Biochemical and Biophysical Research Communications

Année:

2008

Langue:

english

Fichier:

PDF, 891 KB

english, 2008

37

Brain nicotinic receptors: structure and regulation, role in learning and reinforcement

Jean-Pierre Changeux, Daniel Bertrand, Pierre-Jean Corringer, Stanislas Dehaene, Stuart Edelstein, Clément Léna, Nicolas Le Novère, Lisa Marubio, Marina Picciotto, Michele Zoli

Journal:

Brain Research Reviews

Année:

1998

Langue:

english

Fichier:

PDF, 713 KB

english, 1998

38

Ion Channels, a Practical Approach

Nicolas Le Novère, Lisa Marubio, Clément Léna

Journal:

Trends in Neurosciences

Année:

1996

Langue:

english

Fichier:

PDF, 69 KB

english, 1996

39

Ligand Depletion in vivo Modulates the Dynamic Range of Cooperative Signal Transduction

Edelstein, Stuart J., Stefan, Melanie, Le Novère, Nicolas

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 34 KB

english, 2010

40

Improved Secondary Structure Predictions for a Nicotinic Receptor Subunit: Incorporation of Solvent Accessibility and Experimental Data into a Two-Dimensional Representation

Le Novère, Nicolas, Corringer, Pierre-Jean, Changeux, Jean-Pierre

Journal:

Biophysical Journal

Année:

1999

Langue:

english

Fichier:

PDF, 1.83 MB

english, 1999

41

MELTING, a flexible platform to predict the melting temperatures of nucleic acids

Marine Dumousseau, Nicolas Rodriguez, Nick Juty, Nicolas Le Novère

Journal:

BMC Bioinformatics

Année:

2012

Langue:

english

Fichier:

PDF, 589 KB

english, 2012

42

LibKiSAO: a Java library for Querying KiSAO

Anna Zhukova, Richard Adams, Camille Laibe, Nicolas Le Novère

Journal:

BMC Research Notes

Année:

2012

Langue:

english

Fichier:

PDF, 850 KB

english, 2012

43

Normal Mode Analysis Suggests a Quaternary Twist Model for the Nicotinic Receptor Gating Mechanism

Taly, Antoine, Delarue, Marc, Grutter, Thomas, Nilges, Michael, Le Novère, Nicolas, Corringer, Pierre-Jean, Changeux, Jean-Pierre

Journal:

Biophysical Journal

Année:

2005

Langue:

english

Fichier:

PDF, 1018 KB

english, 2005

44

Cooperativity of Allosteric Receptors

Edelstein, Stuart J., Le Novère, Nicolas

Journal:

Journal of Molecular Biology

Année:

2013

Langue:

english

Fichier:

PDF, 310 KB

english, 2013

45

Approches théoriques et pratiques en hybridation in situ et autoradiographie réceptorielle

Le Novère, Nicolas

Journal:

Annales de l'Institut Pasteur / Actualités

Année:

1998

Langue:

french

Fichier:

PDF, 1.95 MB

french, 1998

46

Diversity and Distribution of Nicotinic Acetylcholine Receptors in the Locus Ceruleus Neurons

Clement Lena, Alban de Kerchove d'Exaerde, Matilde Cordero-Erausquin, Nicolas Le Novere, Maria del Mar Arroyo-Jimenez and Jean-Pierre Changeux

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.47 MB

english, 1999

47

Schizophrenic: forever young?

Benedetta Frida Baldi,Christine Hoyer,Nicolas Le Novère

Journal:

Genome Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 266 KB

english, 2010

48

Calcium Input Frequency, Duration and Amplitude Differentially Modulate the Relative Activation of Calcineurin and CaMKII

Li, Lu, Stefan, Melanie I., Le Novère, Nicolas, Feng, Zhong-Ping

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2012

49

Structural Analysis and Stochastic Modelling Suggest a Mechanism for Calmodulin Trapping by CaMKII

Stefan, Melanie I., Marshall, David P., Le Novère, Nicolas, Chan, Christina

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2012

50

Modulation of Calmodulin Lobes by Different Targets: An Allosteric Model with Hemiconcerted Conformational Transitions

Lai, Massimo, Brun, Denis, Edelstein, Stuart J., Le Novère, Nicolas, Schlessinger, Avner

Journal:

PLoS Computational Biology

Année:

2015

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2015